Structure of PDB 4biv Chain A

Receptor sequence
>4bivA (length=269) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KPARKLKNAADEVAQGNLRQHPELEAGPQEFLAAGASFNQMVTALERMMT
SQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSM
INDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFP
PGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDD
GPGVSPEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKA
EDSPLGGLRLVIWLPLYKR
3D structure
PDB4biv Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A N360 R363 Y364 I399 R405 T406 G418 G420 L421 N173 R176 Y177 I212 R218 T219 G231 G233 L234
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4biv, PDBe:4biv, PDBj:4biv
PDBsum4biv
PubMed24492262
UniProtP0AE82|CPXA_ECOLI Sensor histidine kinase CpxA (Gene Name=cpxA)

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