Structure of PDB 4bdv Chain A

Receptor sequence
>4bdvA (length=612) Species: 9606 (Homo sapiens) [Search protein sequence]
ATRRYYLGAVELSWDYVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQ
AEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDK
VFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALL
VCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSPKMHTVNGYVNRSLPGL
IGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISPITFLT
AQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPKHPKTWVHYIAA
EEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKT
REAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYS
RRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVN
MERDLASGLIGPLLICYKERNVILFSVFDENRSWYLTENIQRFLPNPAGV
QLEDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSIGAQTDFLSV
FFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCHNSDFRNRG
MTALLKVSSCDK
3D structure
PDB4bdv Evaluation of the Metal Binding Sites in a Recombinant Coagulation Factor Viii Identifies Two Sites with Unique Metal Binding Properties.
ChainA
Resolution3.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H267 C310 H315 H222 C265 H270
BS02 CA A K107 D116 D125 D126 K80 D89 D98 D99
Gene Ontology
Molecular Function
GO:0005507 copper ion binding

View graph for
Molecular Function
External links
PDB RCSB:4bdv, PDBe:4bdv, PDBj:4bdv
PDBsum4bdv
PubMed23435097
UniProtP00451|FA8_HUMAN Coagulation factor VIII (Gene Name=F8)

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