Structure of PDB 4bc7 Chain A

Receptor sequence
>4bc7A (length=555) Species: 10141 (Cavia porcellus) [Search protein sequence]
GIIPKKRQELMKWNGWGYNDSKFFLNKKGQLELTGKRYPLSGVALPTFKD
WIQNTFGINLDHKTDTPPSIVNEDFLHELKKTNISYSQEADDRVFRAHGH
CLHEIFLLREGMFERIPDIVLWPTCHDDVVKIVNLACKYNLCIIPIGGGT
SVSYGLMCPADETRTIISLDTSQMNRILWVDENNLTAHVEAGITGQELER
QLKESGYCTGHEPDSLEFSTVGGWISTRASGMKKNIYGNIEDLVVHMKVV
TPRGVIEKSCQGPRMSTGPDIHHFIMGSEGTLGVITEATIKIRPTPEYQK
YGSVAFPNFEQGVACLREIAKQRCAPASIHLMDNQQFQFGHALKPQVSSI
FTSGFDPNQLSVATLLFEGDREKVLQHEKQVYDIAAKFGGLAAGEDNGQR
GYLLTYVIAYMRDLGLEYYIIGESFETSAPWDRVVDLCRNVKERIRRECK
EKGVQFPPLSTCRVTQTYDAGACIYFYFAFNYRGISDPLAVFEQTEAAAR
EEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKSVKDYVDPTNIFG
NRNLL
3D structure
PDB4bc7 Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.26: alkylglycerone-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A P234 G236 G237 G238 T239 S240 V241 L245 P302 D303 S304 S308 T309 G312 W313 S315 T316 A318 S319 E368 V373 I374 H616 P145 G147 G148 G149 T150 S151 V152 L156 P213 D214 S215 S219 T220 G223 W224 S226 T227 A229 S230 E279 V284 I285 H513
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008609 alkylglycerone-phosphate synthase activity
GO:0016740 transferase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0006629 lipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0008611 ether lipid biosynthetic process
Cellular Component
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bc7, PDBe:4bc7, PDBj:4bc7
PDBsum4bc7
PubMed23112191
UniProtP97275|ADAS_CAVPO Alkyldihydroxyacetonephosphate synthase, peroxisomal (Gene Name=AGPS)

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