Structure of PDB 4bc4 Chain A

Receptor sequence
>4bc4A (length=525) Species: 9606 (Homo sapiens) [Search protein sequence]
RRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHK
DGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKA
GAQQALTSLSPDLRLHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGA
QALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAASLFLG
SYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPHLEEKLSPPVPSCSVVG
AISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLF
LWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWS
DFSKALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDV
EVRALIEGQFMAKRIHAEGLGYRVMSKTKILATGGASHNREILQVLADVF
DAPVYVIDTANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRLAATPS
PGASQVYEALLPQYAKLEQRILSQT
3D structure
PDB4bc4 Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
ChainA
Resolution1.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.17: xylulokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XUL A Q97 Q98 H99 W137 R170 D280 N281 Q91 Q92 H93 W131 R164 D274 N275
Gene Ontology
Molecular Function
GO:0004856 D-xylulokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005997 xylulose metabolic process
GO:0005998 xylulose catabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0016310 phosphorylation
GO:0019640 D-glucuronate catabolic process to D-xylulose 5-phosphate
GO:0042732 D-xylose metabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bc4, PDBe:4bc4, PDBj:4bc4
PDBsum4bc4
PubMed23179721
UniProtO75191|XYLB_HUMAN Xylulose kinase (Gene Name=XYLB)

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