Structure of PDB 4bb2 Chain A

Receptor sequence
>4bb2A (length=332) Species: 9606 (Homo sapiens) [Search protein sequence]
HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGH
TRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLEL
LESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGL
DSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSST
ISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWS
AGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQ
LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT
3D structure
PDB4bb2 Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
ChainA
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS A C60 R64 C48 R52
BS02 STR A S19 R260 N264 S7 R243 N247 PDBbind-CN: -logKd/Ki=7.07,Kd~85nM
BindingDB: Ki=42nM
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
Cellular Component
GO:0005615 extracellular space

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Molecular Function
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Cellular Component
External links
PDB RCSB:4bb2, PDBe:4bb2, PDBj:4bb2
PDBsum4bb2
PubMed23300763
UniProtP08185|CBG_HUMAN Corticosteroid-binding globulin (Gene Name=SERPINA6)

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