Structure of PDB 4b61 Chain A

Receptor sequence

>4b61A (length=429) Species: 208964 (Pseudomonas aeruginosa PAO1)

PKNFGLDVKITGESENDRDLGTAPGGTLNDIGIDLRPWAFGQWGDWSAYF
MGQAVAATDTIETDTLQNDGREPDKSYLAAREFWVDYAGLTAYPGEHLRF
GRQRLREDSGQWQDTNIEALNWSFETTLLNAHAGVAQRFSEYRTDLDELA
PEDKDRTHVFGDISTQWAPHHRIGVRIHHADDSGHLRRPGEEVDNLDKTY
TGQLTWLGIEATGDAYNYRSSMPLNYWASATWLTGDRDNLTTTTVDDRRI
ATGKQSGDVNAFGVDLGLRWNIDEQWKAGVGYARGSGGGKDGEEQFQQTG
LESNRSNFTGTRSRVHRFGEAFRGELSNLQAATLFGSWQLREDYDASLVY
HKFWRVDDDSDIGTSGINAALQPGEKDIGQELDLVVTKYFKQPSALIRFR
GGLFKPGDAYGPGTDSTMHRAFVDFIWRF

3D structure

• PDB: 4b61 A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
• Chain: A
• Resolution: 2.402 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	78M	A	N41 F78 G79 F88 F131 W132	N3 F40 G41 F50 F83 W84
BS02	78M	A	L430 G462 G463 L464 H480	L382 G401 G402 L403 H419
BS03	78M	A	D321 W324	D273 W276
BS04	78M	A	F148 E166 A167	F100 E118 A119
BS05	MG	A	A136 T139 Y141 E144	A88 T91 Y93 E96
BS06	CU	A	D55 D57 A61 G63	D17 D19 A23 G25
BS07	78N	A	G384 Y392	G336 Y344
BS08	78N	A	Y392 I458 F460	Y344 I397 F399
BS09	78M	A	I225 T253	I177 T205
BS10	78M	A	N308 A309 E342	N260 A261 E294

Gene Ontology

Biological Process

• GO:0042121 alginic acid biosynthetic process

Cellular Component

• GO:0009279 cell outer membrane

External links

• PDB: RCSB:4b61, PDBe:4b61, PDBj:4b61
• PDBsum: 4b61
• PubMed: 25084326
• UniProt: P18895|ALGE_PSEAE Alginate production protein AlgE (Gene Name=algE)