Structure of PDB 4b48 Chain A

Receptor sequence
>4b48A (length=348) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MAKVRIYQLAKELGMETQELLELLDQMGVAYKSHASTLEEKDAEAVRELV
KEQRGLQEKLAEEERRKSLPRRPPVVVIMGHVDHGKTTLLDYLRKSRIAE
KEAGGITQHVGAFEVKTPQGTVVFIDTPGHEARGAKVADIAVIVIAADDG
IMPQTEEAIAHAKAAGAKLIFAINKIDLPQADPEKVKRQLMERGFVPEEY
GGDAIVIPISAKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILESKL
DKQAGIIANMLVQEGTFRVGDYVVAGEAYGRIRAMMDADGNQRKEAGPGS
AVQVLGFQELPHAGDVVEWVPDLEAAKEIAEERKEERKAREEEEKARR
3D structure
PDB4b48 Structure of the Protein Core of Translation Initiation Factor 2 in Apo, GTP-Bound and Gdp-Bound Forms
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D83 K86 T87 T107 H130
Catalytic site (residue number reindexed from 1) D83 K86 T87 T107 H130
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP A H81 V82 D83 G85 K86 T87 T88 N180 K181 D183 L184 S216 A217 K218 H81 V82 D83 G85 K86 T87 T88 N174 K175 D177 L178 S210 A211 K212
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006413 translational initiation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4b48, PDBe:4b48, PDBj:4b48
PDBsum4b48
PubMed23695237
UniProtP48515|IF2_THET8 Translation initiation factor IF-2 (Gene Name=infB)

[Back to BioLiP]