Structure of PDB 4b44 Chain A

Receptor sequence
>4b44A (length=347) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
AKVRIYQLAKELGMETQELLELLDQMGVAYKSHASTLEEKDAEAVRELVK
EQRGLQEKLAEEERRKSLPRRPPVVVIMGHVDHGKTTLLDYLRKSRIAEK
EAGGITQHVGAFEVKTPQGTVVFIDTPGHEARGAKVADIAVIVIAADDGI
MPQTEEAIAHAKAAGAKLIFAINKIDLPQADPEKVKRQLMERGFVPEEYG
GDAIVIPISAKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILESKLD
KQAGIIANMLVQEGTFRVGDYVVAGEAYGRIRAMMDADGNQRKEAGPGSA
VQVLGFQELPHAGDVVEWVPDLEAAKEIAEERKEERKAREEEEKARR
3D structure
PDB4b44 Molecular Basis of GTP Hydrolysis by Bacterial Translation Initiation Factor If2
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D83 K86 T87 T107 H130
Catalytic site (residue number reindexed from 1) D82 K85 T86 T106 H129
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A D83 G85 K86 T87 T88 N180 K181 D183 S216 A217 K218 D82 G84 K85 T86 T87 N173 K174 D176 S209 A210 K211
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006413 translational initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:4b44, PDBe:4b44, PDBj:4b44
PDBsum4b44
PubMed
UniProtP48515|IF2_THET8 Translation initiation factor IF-2 (Gene Name=infB)

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