Structure of PDB 4b23 Chain A

Receptor sequence
>4b23A (length=206) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
KDSDYKRAEKHLSSIDNKWSSLVKKVGPCTLTPHPEHAPYEGIIRAITSQ
KLSDAATNSIINKFCTQCSDNDEFPTPKQIMETDVETLHECGFSKLKSQE
IHIVAEAALNKQIPSKSEIEKMSEEELMESLSKIKGVKRWTIEMYSIFTL
GRLDIMPADDSTLKNEAKEFFGLSSKPQTEEVEKLTKPCKPYRTIAAWYL
WQIPKL
3D structure
PDB4b23 Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.21: DNA-3-methyladenine glycosylase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Q52 K53 L98 E102 K137 G138 K140 W142 T143 K207 L208 Q50 K51 L96 E100 K135 G136 K138 W140 T141 K205 L206
BS02 dna A K53 L54 S55 A58 S61 G94 S96 K97 K99 K51 L52 S53 A56 S59 G92 S94 K95 K97
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003905 alkylbase DNA N-glycosylase activity
GO:0032131 alkylated DNA binding
GO:0140431 DNA-(abasic site) binding
Biological Process
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006285 base-excision repair, AP site formation
GO:0006289 nucleotide-excision repair
GO:0006307 DNA alkylation repair
Cellular Component
GO:0005634 nucleus
GO:0032993 protein-DNA complex

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Cellular Component
External links
PDB RCSB:4b23, PDBe:4b23, PDBj:4b23
PDBsum4b23
PubMed23245849
UniProtO94468|MAG2_SCHPO Alkylbase DNA glycosidase-like protein mag2 (Gene Name=mag2)

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