Structure of PDB 4b17 Chain A

Receptor sequence
>4b17A (length=357) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPD
DGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKG
GELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHV
FFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFI
PADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMD
TGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRE
TIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTV
HVRRIWA
3D structure
PDB4b17 Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.186: 23S rRNA (cytidine(2498)-2'-O)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A S188 G219 C221 P222 G224 W225 D240 D260 G261 F262 D277 M278 S188 G219 C221 P222 G224 W225 D240 D260 G261 F262 D277 M278
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0070677 rRNA (cytosine-2'-O-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4b17, PDBe:4b17, PDBj:4b17
PDBsum4b17
PubMed22923526
UniProtP0ADR6|RLMM_ECOLI Ribosomal RNA large subunit methyltransferase M (Gene Name=rlmM)

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