Structure of PDB 4ayx Chain A

Receptor sequence
>4ayxA (length=571) Species: 9606 (Homo sapiens) [Search protein sequence]
LPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNP
TVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFS
SILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVG
ISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQL
AEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATG
LSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYS
ELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPA
RPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISL
DGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEI
QRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPK
ILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAV
LDQGKITEYGKHEELLSKPNG
3D structure
PDB4ayx Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLY A R170 Y234 R17 Y81
BS02 MG A S534 Q575 S381 Q422
BS03 ACP A Y501 S529 G530 G532 K533 S534 T535 Y348 S376 G377 G379 K380 S381 T382 PDBbind-CN: -logKd/Ki=3.70,Ki=0.2mM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ayx, PDBe:4ayx, PDBj:4ayx
PDBsum4ayx
PubMed23716676
UniProtQ9NRK6|ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial (Gene Name=ABCB10)

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