Structure of PDB 4ay7 Chain A

Receptor sequence
>4ay7A (length=337) Species: 2209 (Methanosarcina mazei) [Search protein sequence]
EFTLKTRLLAALKGEPVDKVPVCSVTQTGIVELMDVVGAPWPEAHTNPEL
MAKLALANHELSGLEAVRLPYCLTVLVEAMGCEINMGTKNRQPSVTGHPY
PKDLEGAAVPADLLQRGRIPVVLEAIKIIREKVGPDVPIVGGMEGPVTVA
SDLVSVKSFMKWSIKKTDLLEQALDIATEASIIYANAMVEAGADVIAIAD
PVASPDLMSPDSFRQFLKSRLQKFASSVNSVTVLHICGNVNPILSDMADC
GFEGLSVEEKIGSAKKGKEVIGTRARLVGNVSSPFTLLPGPVDKIKAEAK
EALEGGIDVLAPGCGIAPMTPLENVKALVAARDEFYA
3D structure
PDB4ay7 Structure of the Corrinoid:Coenzyme M Methyltransferase Mtaa from Methanosarcina Mazei
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T31 T33 V42 C77 P151
Catalytic site (residue number reindexed from 1) T26 T28 V37 C72 P146
Enzyme Commision number 2.1.1.247: [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H240 C242 H235 C237
Gene Ontology
Molecular Function
GO:0004853 uroporphyrinogen decarboxylase activity
GO:0008168 methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0015948 methanogenesis
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4ay7, PDBe:4ay7, PDBj:4ay7
PDBsum4ay7
PubMed23090404
UniProtQ8PXZ6

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