Structure of PDB 4au2 Chain A

Receptor sequence
>4au2A (length=367) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
MLSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLG
GKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNVTWKLGSRLYGPSS
VSFAEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVT
KDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHR
TGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQ
LKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSR
MSGKKDLYLASVFHATAFEWDTEGNPFDLRSPKLFYADHPFIFLVRDTQS
GSLLFIGRLVRPKGDKM
3D structure
PDB4au2 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M218 R222 M225 H238 L381 Y383 D385 M179 R183 M186 H199 L334 Y336 D338
BS02 peptide A R228 L381 Y383 R189 L334 Y336
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005518 collagen binding
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4au2, PDBe:4au2, PDBj:4au2
PDBsum4au2
PubMed22847422
UniProtC7C419

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