Structure of PDB 4are Chain A

Receptor sequence
>4areA (length=678) Species: 1498 (Hathewaya histolytica) [Search protein sequence]
NLYFQTMYDFEYLNGLSYTELTNLIKNIKWNQINGLFNYSTGSQKFFGDK
NRVQAIINALQESGRTYTANDMKGIETFTEVLRAGFYLGYYNDGLSYLND
RNFQDKCIPAMIAIQKNPNFKLGTAVQDEVITSLGKLIGNASANAEVVNN
CVPVLKQFRENLNQYAPDYVKGTAVNELIKGIEFDFSGAAYEKDVKTMPW
YGKIDPFINELKALGLYGNITSATEWASDVGIYYLSKFGLYSTNRNDIVQ
SLEKAVDMYKYGKIAFVAMERITWDYDGIGSNGKKVDHDKFLDDAEKHYL
PKTYTFDNGTFIIRAGDKVSEEKIKRLYWASREVKSQFHRVVGNDKALEV
GNADDVLTMKIFNSPEEYKFNTNINGVSTDNGGLYIEPRGTFYTYERTPQ
QSIFSLEELFRHEYTHYLQARYLVDGLWGQGPFYEKNRLTWFDEGTAEFF
AGSTRTSGVLPRKLILGYLAKDKVDHRYSLKKTLNSGYDDSDWMFYNYGF
AVAHYLYEKDMPTFIKMNKAILNTDVKSYDEIIKKLSDDANKNTEYQNHI
QELVDKYQGAGIPLVSDDYLKDHGYKKASEVYSEISKAASLTNTSVTAEK
SQYFNTFTLRGTYTGETSKGEFKDWDEMSKKLDGTLESLAKNSWSGYKTL
TAYFTNYRVTSDNKVQYDVVFHGVLTDN
3D structure
PDB4are Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T.
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H523 H527 E555 H412 H416 E444
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4are, PDBe:4are, PDBj:4are
PDBsum4are
PubMed23703618
UniProtQ9X721|COLG_HATHI Collagenase ColG (Gene Name=colG)

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