Structure of PDB 4apx Chain A

Receptor sequence
>4apxA (length=208) Species: 10090 (Mus musculus) [Search protein sequence]
MQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGE
EASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQV
GDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQ
PPSPFFAIDSARGIVTVIQELDYEVTQAYQLTVNATDQDKTRPLSTLANL
AIIITDLE
3D structure
PDB4apx Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N4 R5 D37 D39 D41 D87 N4 R5 D37 D39 D41 D87
BS02 CA A E22 E74 D102 V103 D105 D138 E22 E74 D102 V103 D105 D138
BS03 CA A E22 D72 E74 D105 E22 D72 E74 D105
BS04 CA A N104 N106 D136 D138 G142 D187 N104 N106 D136 D138 G142 D187
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:4apx, PDBe:4apx, PDBj:4apx
PDBsum4apx
PubMed23135401
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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