Structure of PDB 4anj Chain A

Receptor sequence
>4anjA (length=995) Species: 6100,9823 [Search protein sequence]
GKPVWAPHPTDGFQVGNIVDIGPDSLTIEPLKTFLALINQVFPAEEDSKK
DVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIY
SSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESGAGK
TENTKFVLRYLTESYGTIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFV
EIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIR
ERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSLKDPL
LDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEECNLKNK
STQALEYCAELLGLDQDDLRVSLTTRVKVPLKVEQANNARDALAKTVYSH
LFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKL
QQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEARLVGILDILD
EENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSKLAIHRNIRDDEGFIIR
HFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESFISVGNK
FKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVS
VLDLMQGGFPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNE
IDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLICSRWKKV
QWCSLSVIKLKNKIKYRAEAVSKGEELFTGVVPILVELDGDVNGHKFSVS
GEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFVQCFARYPDHMRQHDF
FKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKED
GNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQ
QNTPIGDGPVLLPDNHYLSYQSALSKDPNEKRDHMVLLEFVTAAG
3D structure
PDB4anj Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S153 G154 T158 N200 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S146 G147 T151 N190 S193 S194 G429 E431
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N98 P99 F101 G154 G156 K157 T158 E159 F163 N200 N91 P92 F94 G147 G149 K150 T151 E152 F156 N190
BS02 MG A T158 S204 T151 S194
BS03 ALF A S153 K157 N200 S203 S204 G459 S146 K150 N190 S193 S194 G429
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0008218 bioluminescence
Cellular Component
GO:0005575 cellular_component
GO:0016459 myosin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4anj, PDBe:4anj, PDBj:4anj
PDBsum4anj
PubMed22940248
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q29122|MYO6_PIG Unconventional myosin-VI (Gene Name=MYO6)

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