Structure of PDB 4am3 Chain A

Receptor sequence
>4am3A (length=622) Species: 190650 (Caulobacter vibrioides CB15) [Search protein sequence]
GSMFDIKRKTIEWGGKTLVLETGRIARQADGAVLATMGETVVLATAVFAK
SQKPGQDFFPLTVNYQEKTFAAGKIPGGFFKREGRPSEKETLVSRLIDRP
IRPLFVKGFKNEVQVVVTVLQHDLENDPDILGMVAASAALCLSGAPFMGP
IGAARVGWVDGAYVLNPTLDEMKESKMDLVVAGTADAVMMVESEIQELSE
EIVLGGVNFAHQQMQAVIDAIIDLAEHAAKEPFAFEPEDTDAIKAKMKDL
VGADIAAAYKIQKKQDRYEAVGAAKKKAIAALGLSDENPTGYDPLKLGAI
FKELEADVVRRGILDTGLRIDGRDVKTVRPILGEVGILPRTHGSALFTRG
ETQAIVVATLGTGDDEQFIDALEGTYKESFLLHYNFPPYSVGETGRMGSP
GRREIGHGKLAWRALRPMLPTKEDFPYTIRLVSEITESNGSSSMATVCGS
SLAMMDAGVPLVRPVSGIAMGLILEQDGFAVLSDILGDEDHLGDMDFKVA
GTSEGLTSLQMDIKIAGITPAIMEQALAQAKEGRAHILGEMNKAMDAPRA
DVGDFAPKIETINIPTDKIREVIGSGGKVIREIVATTGAKVDINDDGVVK
VSASDGAKIKAAIDWIKSITDE
3D structure
PDB4am3 Crystal Structure of Caulobacter Crescentus Polynucleotide Phosphorylase Reveals a Mechanism of RNA Substrate Channelling and RNA Degradosome Assembly.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A G396 S397 G398 S399
BS02 rna A D368 R568 I571 S573 G574 G575 I578 D370 R570 I573 S575 G576 G577 I580
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4am3, PDBe:4am3, PDBj:4am3
PDBsum4am3
PubMed22724061
UniProtQ9AC32|PNP_CAUVC Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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