Structure of PDB 4ags Chain A

Receptor sequence
>4agsA (length=445) Species: 5671 (Leishmania infantum) [Search protein sequence]
RALKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRE
TVPTLEVGNADKRFMFESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFL
AQVGDFIGAAHGLLRDPLSGEKRKAMDDNAAYVDGLLAANQTTGPYYCDG
EFTMADVALVPFLVRLKPALMYYAGYDVFCKAPRMKALWAAAAQRASVRE
TSPTAAQCIENYRHLVPESAPMMGANGGHVLYSNLFCPFVDRARLASELR
KFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQYIDC
VATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQ
WAAGELEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGG
YDLFAHFPLLNGLAEAGMATPEAKSVFRTLEEYKEHIRKRQRRAQ
3D structure
PDB4ags Leishmania Tdr1 Structure, a Unique Trimeric Glutathione Transferase Capable of Deglutathionylation and Antimonial Prodrug Activation.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A C240 F242 T279 V280 E293 S294 C237 F239 T276 V277 E290 S291
BS02 GSH A C14 F16 L38 R39 T54 V55 E70 S71 C11 F13 L35 R36 T51 V52 E67 S68
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4ags, PDBe:4ags, PDBj:4ags
PDBsum4ags
PubMed22753509
UniProtA4I8P2

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