Structure of PDB 4ad9 Chain A

Receptor sequence
>4ad9A (length=288) Species: 9606 (Homo sapiens) [Search protein sequence]
MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEP
AIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYC
IKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHM
ALLLEEENAIFSGDCILGEGTTVFEDLYDYMNSLKELLKIKADIIYPGHG
PVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVMELVKIIYKNTP
ENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL
3D structure
PDB4ad9 Identification of Lactb2, a Metallo-Beta-Lactamase Protein, as a Human Mitochondrial Endoribonuclease
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.27.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D81 H82 D164 H199 D81 H82 D164 H199
BS02 ZN A H77 H79 H145 D164 H77 H79 H145 D164
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003727 single-stranded RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4ad9, PDBe:4ad9, PDBj:4ad9
PDBsum4ad9
PubMed26826708
UniProtQ53H82|LACB2_HUMAN Endoribonuclease LACTB2 (Gene Name=LACTB2)

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