Structure of PDB 4ad2 Chain A

Receptor sequence
>4ad2A (length=345) Species: 657309 (Bacteroides xylanisolvens XB1A) [Search protein sequence]
TELDYDTFCFYYDWYGSEAIDGQYRHWAHAIAPDPNGGSGQNPGTIPGTQ
ESIASNFYPQLGRYSSSDPNILTKHMDMFVMARTGVLALTWWNEQDETEA
KRIGLILDAADKKKIKVCFHLEPYPSRNVQNLRENIVKLITRYGNHPAFY
RKDGKPLFFIYDSYLIEPSEWEKLLSPGGSITIRNTAYDALMIGLWTSSP
TVQRPFILNAHFDGFYTYFAATGFTYGSTPTNWVSMQKWAKENGKIFIPS
VGPGYIDTRIRPWNGSVIRTRTDGQYYDAMYRKAIEAGVSAISITSFNEW
HEGSQIEPAVPYTSSEFTYLDYENREPDYYLTRTAYWVGKFRESK
3D structure
PDB4ad2 Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.130: glycoprotein endo-alpha-1,2-mannosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A H63 R295 E333 H335 E336 H29 R261 E299 H301 E302 PDBbind-CN: -logKd/Ki=6.20,Kd=625nM
BS02 IFM A Y46 W126 H154 E156 Y195 Y252 E333 E336 Y12 W92 H120 E122 Y161 Y218 E299 E302 PDBbind-CN: -logKd/Ki=6.20,Kd=625nM
Gene Ontology
Molecular Function
GO:0004559 alpha-mannosidase activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4ad2, PDBe:4ad2, PDBj:4ad2
PDBsum4ad2
PubMed22219371
UniProtD6D1V7

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