Structure of PDB 4ac0 Chain A

Receptor sequence
>4ac0A (length=197) Species: 562 (Escherichia coli) [Search protein sequence]
SRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWHVKNKRAL
LDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHL
GTRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEH
QVAKEERESMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKC
3D structure
PDB4ac0 Tetr(B) in Complex with Minocycline and Magnesium
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MIY A H64 N82 F86 H100 L113 Q116 H63 N81 F85 H99 L112 Q115
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:4ac0, PDBe:4ac0, PDBj:4ac0
PDBsum4ac0
PubMed
UniProtP04483|TETR2_ECOLX Tetracycline repressor protein class B from transposon Tn10 (Gene Name=tetR)

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