Structure of PDB 4a9j Chain A

Receptor sequence
>4a9jA (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
VTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMG
TIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFL
QKVASMPQEEQE
3D structure
PDB4a9j Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYL A V103 L110 N156 I162 V29 L36 N82 I88
External links
PDB RCSB:4a9j, PDBe:4a9j, PDBj:4a9j
PDBsum4a9j
PubMed22136404
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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