Structure of PDB 4a14 Chain A

Receptor sequence
>4a14A (length=296) Species: 9606 (Homo sapiens) [Search protein sequence]
EEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVL
AEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEDEQGI
VPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLR
EDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTHLSSRSHTVFTVTL
EQRGQLLVSKFHFVDLAGSERVQINSSLLALGNVISALGDPQRRGSHIPY
RDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQ
3D structure
PDB4a14 Structural Insights Into Human Kif7, a Kinesin Involved in Hedgehog Signalling.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R18 R20 P21 T93 G94 G96 K97 T98 Y99 R10 R12 P13 T85 G86 G88 K89 T90 Y91
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:4a14, PDBe:4a14, PDBj:4a14
PDBsum4a14
PubMed22281744
UniProtQ2M1P5|KIF7_HUMAN Kinesin-like protein KIF7 (Gene Name=KIF7)

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