Structure of PDB 3zyz Chain A

Receptor sequence

>3zyzA (length=713) Species: 51453 (Trichoderma reesei)

VVPPAGTPWGTAYDKAKAALAKLNLQDKVGIVSGVGWNGGPCVGNTSPAS
KISYPSLCLQDGPLGVRYSTGSTAFTPGVQAASTWDVNLIRERGQFIGEE
VKASGIHVILGPVAGPLGKTPQGGRNWEGFGVDPYLTGIAMGQTINGIQS
VGVQATAKHYILNEQELNRETISSNPDDRTLHELYTWPFADAVQANVASV
MCSYNKVNTTWACEDQYTLQTVLKDQLGFPGYVMTDWNAQHTTVQSANSG
LDMSMPGTDFNGNNRLWGPALTNAVNSNQVPTSRVDDMVTRILAAWYLTG
QDQAGYPSFNISRNVQGNHKTNVRAIARDGIVLLKNDANILPLKKPASIA
VVGSAAIIGNHARNSPSCNDKGCDDGALGMGWGSGAVNYPYFVAPYDAIN
TRASSQGTQVTLSNTDNTSSGASAARGKDVAIVFITADSGEGYITVEGNA
GDRNNLDPWHNGNALVQAVAGANSNVIVVVHSVGAIILEQILALPQVKAV
VWAGLPSQESGNALVDVLWGDVSPSGKLVYTIAKSPNDYNTRIVSGGSDS
FSEGLFIDYKHFDDANITPRYEFGYGLSYTKFNYSRLSVLSTAKSGPATG
AVVPGGPSDLFQNVATVTVDIANSGQVTGAEVAQLYITYPSSAPRTPPKQ
LRGFAKLNLTPGQSGTATFNIRRRDLSYWDTASQKWVVPSGSFGISVGAS
SRDIRLTSTLSVA

3D structure

• PDB: 3zyz Biochemical Characterization and Crystal Structures of a Fungal Family 3 Beta-Glucosidase, Cel3A from Hypocrea Jecorina.
• Chain: A
• Resolution: 2.1 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): D236 S439
• Catalytic site (residue number reindexed from 1): D236 S439
• Enzyme Commision number: 3.2.1.21: beta-glucosidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BGC	A	D61 R125 K158 H159 Y204 D236 W237 S384 E441	D61 R125 K158 H159 Y204 D236 W237 S384 E441

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0008422 beta-glucosidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds

Biological Process

• GO:0000272 polysaccharide catabolic process
• GO:0005975 carbohydrate metabolic process
• GO:0009251 glucan catabolic process

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3zyz, PDBe:3zyz, PDBj:3zyz
• PDBsum: 3zyz
• PubMed: 25164811
• UniProt: Q12715