Structure of PDB 3zxe Chain A

Receptor sequence
>3zxeA (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
PHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPR
LDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGD
AQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
3D structure
PDB3zxe Inhibition Mechanism of Human Galectin-7 by a Novel Galactose-Benzylphosphate Inhibitor.
ChainA
Resolution1.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PGZ A H33 H49 R53 W69 E72 H30 H46 R50 W66 E69 MOAD: Kd=450uM
PDBbind-CN: -logKd/Ki=3.35,Kd=450uM
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006915 apoptotic process
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:3zxe, PDBe:3zxe, PDBj:3zxe
PDBsum3zxe
PubMed22059385
UniProtP47929|LEG7_HUMAN Galectin-7 (Gene Name=LGALS7)

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