Structure of PDB 3zx7 Chain A

Receptor sequence
>3zx7A (length=296) Species: 6396 (Eisenia fetida) [Search protein sequence]
AEGYEQIEVDVVAVWKEGYVYENRGSTSVDQKITITKGMKNVNSETRTVT
ATHSIGSTISTGDAFEIGSVEVSYSHSHEESQVSMTETEVYESKVIEHTI
TIPPTSKFTRWQLNADVGGADIEYMYLIDEVTPIGGTQSIPQVITSRAKI
IVGRQIILGKTEIRIKHAERKEYMTVVSRKSWPAATLGHSKLFKFVLYED
WGGFRIKTLNTMYSGYEYAYSSDQGGIYFDQGTDNPKQRWAINKSLPLRH
GDVVTFMNKYFTRSGLCYDDGPATNVYCLDKREDKWILEVVGLVPR
3D structure
PDB3zx7 Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition.
ChainA
Resolution2.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PC A R184 K185 S227 Q229 Y233 P277 Y282 R179 K180 S222 Q224 Y228 P272 Y277
BS02 PC A T238 D239 N240 T233 D234 N235
BS03 PC A I133 D134 E135 I128 D129 E130
BS04 PC A D228 F266 S269 C283 L284 D285 D223 F261 S264 C278 L279 D280
Gene Ontology
Biological Process
GO:0006811 monoatomic ion transport
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
GO:0042742 defense response to bacterium
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0044218 other organism cell membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3zx7, PDBe:3zx7, PDBj:3zx7
PDBsum3zx7
PubMed22819216
UniProtO18423|TXL_EISFE Lysenin

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