Structure of PDB 3zqt Chain A

Receptor sequence
>3zqtA (length=250) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]
QPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLV
FNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVD
GLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPI
ARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB3zqt Targeting the Binding Function 3 (Bf3) Site of the Human Androgen Receptor Through Virtual Screening.
ChainA
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TES A L701 L704 N705 M745 M749 F764 T877 M895 L32 L35 N36 M76 M80 F95 T208 M226 BindingDB: IC50=2.7nM,Ki=3.2nM,EC50=1.1nM
BS02 30Z A F673 N727 L830 E837 F4 N58 L161 E168 PDBbind-CN: -logKd/Ki=4.41,IC50=38.8uM
External links
PDB RCSB:3zqt, PDBe:3zqt, PDBj:3zqt
PDBsum3zqt
PubMed22047606
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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