Structure of PDB 3zqs Chain A

Receptor sequence
>3zqsA (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
QFYSSLIEEIGTLGWDKLVYADTCFSTIKLKAEDASGREHLITLKLKAKY
PAESPDYFVDFPVPFCASWTPQSSLISIYSQFLAAIESLKAFWDVMDEID
EKTWVLEPEKPPRSATARRIALGNNVSINIEVDPRHPTMLPECFFLGADH
VVKPLGIKLSRNIHLWDPENSVLQNLKDVLEIDFPA
3D structure
PDB3zqs Structural Analysis of Human Fancl, the E3 Ligase in the Fanconi Anemia Pathway.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRO A S222 T224 S114 T116
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
Biological Process
GO:0036297 interstrand cross-link repair
Cellular Component
GO:0043240 Fanconi anaemia nuclear complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zqs, PDBe:3zqs, PDBj:3zqs
PDBsum3zqs
PubMed21775430
UniProtQ9NW38|FANCL_HUMAN E3 ubiquitin-protein ligase FANCL (Gene Name=FANCL)

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