Structure of PDB 3zqj Chain A

Receptor sequence
>3zqjA (length=944) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
ADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQ
RRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVGT
ITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFLV
LAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHDI
EVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVDEQRFSEKLACPN
GHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELVVPDPDRTLAQ
GAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAKARKAILEGAD
EQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRD
VPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELSIADCADFLNA
LTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAATLSGGEAQRI
RLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLRDLGNTLIVVE
HDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKDSITGAYLSGR
ESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVLTSVTGVSGSG
KSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLVRVDQSPIGRT
PRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGD
GTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEA
AEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
RSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIK
TSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVV
3D structure
PDB3zqj The Biological and Structural Characterization of Mycobacterium Tuberculosis Uvra Provides Novel Insights Into its Mechanism of Action
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C753 C756 C776 C779 C744 C747 C767 C770
BS02 ZN A C121 C124 C257 H261 C120 C123 C248 H252
BS03 ZN A C282 C285 C412 C415 C273 C276 C403 C406
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0009381 excinuclease ABC activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0060543 negative regulation of strand invasion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0009380 excinuclease repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zqj, PDBe:3zqj, PDBj:3zqj
PDBsum3zqj
PubMed21622956
UniProtP9WQK7|UVRA_MYCTU UvrABC system protein A (Gene Name=uvrA)

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