Structure of PDB 3zou Chain A

Receptor sequence
>3zouA (length=274) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
SMIAAYQARCQARVDAALDALFVAPREELQRLYEAMRYSVMNGGKRVRPL
LAYAACEALGGAPQRADAAACAVELIHAYSLVHDDLPAMDDDDLRRGQPT
THRAFDEATAILAADGLQALAFEVLADTRRNPQEHAVCLEMLTRLARAAG
SAGMVGGQAIDLGSVALDQAALEVMHRHKTGALIEASVRLGALASGRAEP
ASLAALERYAEAIGLAFQVQDDILDVPTYPALLGLEAAKGYALELRDLAL
AALDGFPPSADPLRQLARYIVERR
3D structure
PDB3zou Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa
ChainA
Resolution1.55 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D83 D89 D84 D90
BS02 MG A D83 D89 D84 D90
BS03 GPP A S79 D83 R94 V154 Q157 K180 S80 D84 R95 V155 Q158 K179
BS04 6H6 A A3 Q6 V46 Y289 A4 Q7 V47 Y269
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3zou, PDBe:3zou, PDBj:3zou
PDBsum3zou
PubMed25760619
UniProtQ9HWY4

[Back to BioLiP]