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Structure of PDB 3zoa Chain A

Receptor sequence
>3zoaA (length=548) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
PTDTNWFKHAVFYEVLVRAFYDSNADGIGDLRGLTEKLDYIKWLGVDCLW
LPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVTLLDAAHRRGIRIITDL
VMNHTSDQHEWFQESRHNPDGPYGDFYVWSDTSDRYPDARIIFVDTEESN
WTFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMLDVLRFWLDLGIDGFRL
DAVPYLFEREGTNCENLPETHAFLKRCRKAIDDEYPGRVLLAEANQWPAD
VVAYFGDPDTGGDECHMAFHFPLMPRIFMAVRRESRFPISEILAQTPPIP
DTAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPRMKANVGIRRRLAP
LLENDRNQIELFTALLLSLPGSPVLYYGDEIGMGDIIWLGDRDSVRTPMQ
WTPDRNAGFSKATPGRLYLPPNQDAVYGYHSVNVEAQLDSSSSLLNWTRN
MLAVRSRHDAFAVGTFRELGGSNPSVLAYIREVTTDAVLCVNNLSRFPQP
IELNLQQWAGYIPVEMTGYVEFPSIGQLPYLLTLPGHGFYWFQLREPD
3D structure
PDB3zoa The Structure of the Mycobacterium Smegmatis Trehalose Synthase Reveals an Unusual Active Site Configuration and Acarbose-Binding Mode.
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D128 R228 D230 E272 H341 D342
Catalytic site (residue number reindexed from 1) D99 R199 D201 E243 H312 D313
Enzyme Commision number 3.2.1.1: alpha-amylase.
5.4.99.16: maltose alpha-D-glucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AC1 A W476 M480 E553 M554 T555 F577 Y578 W579 W447 M451 E515 M516 T517 F539 Y540 W541
BS02 CA A N132 D200 Y234 L235 E237 N103 D171 Y205 L206 E208
BS03 MG A D51 N53 D55 I57 D59 D22 N24 D26 I28 D30
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004556 alpha-amylase activity
GO:0005509 calcium ion binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0047471 maltose alpha-D-glucosyltransferase activity
Biological Process
GO:0000023 maltose metabolic process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0005978 glycogen biosynthetic process
GO:0005991 trehalose metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3zoa, PDBe:3zoa, PDBj:3zoa
PDBsum3zoa
PubMed23735230
UniProtA0R6E0|TRES_MYCS2 Trehalose synthase/amylase TreS (Gene Name=treS)

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