Structure of PDB 3zjc Chain A

Receptor sequence
>3zjcA (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
SLRIVLVGKTGSGKSATANTILGEEIFDSRIAAQAVTKNCQKASREWQGR
DLLVVDTPGLFDSLDTTCKEISRCIISSCPGPHAIVLVLQLGRYTEEEQK
TVALIKAVFGKSAMKHMVILFTRKEELEGQSFHDFIADADVGLKSIVKEC
GNRCCAFSNSTSKAEKESQVQELVELIEKMVQCNEGAYFSDDIYKDTEER
LKQREEVLRKIYTDQLNEEIKLVEEDKHKSEEEKEKEIKLLKLKYDEKIK
NIREEAERNIFKDVFNRIWKMLSEIWHRFLSKC
3D structure
PDB3zjc Structural Insights Into the Mechanism of Gtpase Activation in the Gimap Family.
ChainA
Resolution3.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A S22 T44 S15 T37
BS02 GNP A T17 G18 G20 K21 S22 A23 S36 R37 I38 V43 T44 R133 E135 S168 N169 T10 G11 G13 K14 S15 A16 S29 R30 I31 V36 T37 R123 E125 S158 N159 PDBbind-CN: -logKd/Ki=5.05,Kd=9uM
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0046039 GTP metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005811 lipid droplet

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3zjc, PDBe:3zjc, PDBj:3zjc
PDBsum3zjc
PubMed23454188
UniProtQ8NHV1|GIMA7_HUMAN GTPase IMAP family member 7 (Gene Name=GIMAP7)

[Back to BioLiP]