Structure of PDB 3zev Chain A

Receptor sequence
>3zevA (length=307) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTLFTLARKKSLQSTVD
YYLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACT
YATALNVVSLSVELYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIP
MLFTMGLQNLSGDGTHPGGLVCTPIVDTATLKVVIQVNTFMSFLFPMLVA
SILNTVIANKLTVMVHQPGRVQALRRGVLVLRAVVIAFVVCWLPYHVRRL
MFCYISDEQWTTFLFDFYHYFYMLTNALVYVSAAINPILYNLVSANFRQV
FLSTLAC
3D structure
PDB3zev Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D54 L55 D56 Y146 V224 T226 R327 F331 C332 I334 D336 W339 F344 Y347 D4 L5 D6 Y93 V171 T173 R248 F252 C253 I255 D257 W260 F265 Y268
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0016492 G protein-coupled neurotensin receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zev, PDBe:3zev, PDBj:3zev
PDBsum3zev
PubMed24453215
UniProtP20789|NTR1_RAT Neurotensin receptor type 1 (Gene Name=Ntsr1)

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