Structure of PDB 3zbr Chain A

Receptor sequence
>3zbrA (length=215) Species: 10090 (Mus musculus) [Search protein sequence]
EKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDE
KLELVSYFGKRPPGVLSCTTKFCDYGKAAGAEEYAQQEVVKRSYGKAFKL
SISALFVTPKTAGAQVVLTDQELQLWPSDLDKPSASEGLPPGSRAHVTLG
CAADVQPVQTGLDLLDILQQVKGGSQGEAVGELPRGKLYSLGKGRWMLSL
TKKMEVKAIFTGYYG
3D structure
PDB3zbr Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family
ChainA
Resolution2.304 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.37: 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A L167 Y168 T232 F235 H309 T311 P320 V321 Y376 L7 Y8 T69 F72 H146 T148 P157 V158 Y213
Gene Ontology
Molecular Function
GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
Biological Process
GO:0009214 cyclic nucleotide catabolic process
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:3zbr, PDBe:3zbr, PDBj:3zbr
PDBsum3zbr
PubMed23831225
UniProtP16330|CN37_MOUSE 2',3'-cyclic-nucleotide 3'-phosphodiesterase (Gene Name=Cnp)

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