Structure of PDB 3x2t Chain A

Receptor sequence
>3x2tA (length=311) Species: 10090 (Mus musculus) [Search protein sequence]
PAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVL
PPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP
QLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTN
LAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAMNEHSSRSH
SIFLINIKQENVETEKKLSGKLYLVDLAGSEKNKSLSALGNVISALAEGT
KTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQR
AKTIKNTVSVN
3D structure
PDB3x2t X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R14 R16 P17 T88 S89 G91 K92 T93 H94 R11 R13 P14 T85 S86 G88 K89 T90 H91
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:3x2t, PDBe:3x2t, PDBj:3x2t
PDBsum3x2t
PubMed25777528
UniProtP28738|KIF5C_MOUSE Kinesin heavy chain isoform 5C (Gene Name=Kif5c)

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