Structure of PDB 3x12 Chain A

Receptor sequence
>3x12A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPW
IEQEGPEYWDGETRNMKASAQTYRENLRNALRYYNQSEAGSHIIQVMYGC
DVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAR
VAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB3x12 The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M5 Y7 E63 N66 M67 T73 N77 N80 Y84 I95 Y99 D114 Y123 T143 W147 V152 Q155 L156 Y159 W167 Y171 M4 Y6 E62 N65 M66 T72 N76 N79 Y83 I94 Y98 D113 Y122 T142 W146 V151 Q154 L155 Y158 W166 Y170
External links
PDB RCSB:3x12, PDBe:3x12, PDBj:3x12
PDBsum3x12
PubMed25480565
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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