Structure of PDB 3x0o Chain A

Receptor sequence
>3x0oA (length=157) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ERTYLYRGRILNLALEGRYEIVEHKPAVAVIALREGRMLFVRQMRPAVGL
APLEIPAGLIEPGEDPLEAARRELAEETGLSGDLTYLFSYFVSPGFTDEK
THVFLAENLKEVEADEDEAIEVVWMRPEEALERHQRGEVEFSATGLVGVL
YYHAFLR
3D structure
PDB3x0o ADP-Ribose Pyrophosphatase Reaction in Crystalline State Conducted by Consecutive Binding of Two Manganese(II) Ions as Cofactors
ChainA
Resolution1.09 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R54 A66 E82 E86 E127
Catalytic site (residue number reindexed from 1) R45 A57 E73 E77 E116
Enzyme Commision number 3.6.1.13: ADP-ribose diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AR6 A I19 R54 A66 G67 L68 E82 E108 I10 R45 A57 G58 L59 E73 E99
BS02 MN A A66 E86 A57 E77
BS03 MN A E82 E86 E73 E77
Gene Ontology
Molecular Function
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006753 nucleoside phosphate metabolic process
GO:0019693 ribose phosphate metabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3x0o, PDBe:3x0o, PDBj:3x0o
PDBsum3x0o
PubMed26979298
UniProtQ5SKW5

[Back to BioLiP]