Structure of PDB 3x0d Chain A

Receptor sequence
>3x0dA (length=624) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
DYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLD
IGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVIS
ERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVV
PSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSE
MKTHEFRELSEPIVAFKFDFEHEEKIIFDESFVREAVAHSSGTIDALLMW
WDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTF
EIVCNHDEFSLWFSNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKF
KDEVDKLSKGLHVATVGEGSFLGLLAAKTAKRVTIIDGNERFRDIFFKYI
HYYKLTNVEIIEKVTSLTDSPDIVLAEPFYMSAMNPWNHLRFLYDVEVLK
MMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTK
ARTATDAIVDEQSLWEYAGIVKGDAVEILRFPIDGRVSSQKCVVNIDNMS
SSNAIPMWMEWEFGGINLSTGLLSISSAGVPEWNKGYKQGVYFPITALRN
DKSLCLHALFDKSTGDINFQFGKS
3D structure
PDB3x0d Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats
ChainA
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E140 E149
Catalytic site (residue number reindexed from 1) E120 E129
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A M36 R42 I71 G72 T73 L78 E94 V95 R122 S123 E140 V141 M16 R22 I51 G52 T53 L58 E74 V75 R102 S103 E120 V121
BS02 ZN A C207 C345 H350 C187 C325 H330
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0006479 protein methylation
GO:0018216 peptidyl-arginine methylation
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3x0d, PDBe:3x0d, PDBj:3x0d
PDBsum3x0d
PubMed24726727
UniProtQ9XW42|ANM7_CAEEL Protein arginine N-methyltransferase 7 (Gene Name=prmt-7)

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