Structure of PDB 3wxb Chain A

Receptor sequence
>3wxbA (length=269) Species: 9031 (Gallus gallus) [Search protein sequence]
SSGLVPRGSHMGELRVRSVLVTGANRGIGLGFVQHLLALSNPPEWVFATC
RDPKGQRAQELQKLASKHPNLVIVPLEVTDPASIKAAAASVGERLKGSGL
NLLINNAGIARANTIDNETLKDMSEVYTTNTIAPLLLSQAFLPMLKKAAQ
ENPGSGLSCSKAAIINISSTAGSIQDLYLWQYGQALSYRCSKAALNMLTR
CQSMGYREHGIFCVALHPGWVKTDMGGTLEDKSRVTVDESVGGMLKVLSN
LSEKDSGAFLNWEGKVMAW
3D structure
PDB3wxb A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure.
ChainA
Resolution1.98 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.184: carbonyl reductase (NADPH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP A G13 N15 R16 G17 I18 R41 R47 E67 V68 N96 G98 I99 I157 S159 Y178 K182 P208 G209 W210 V211 T213 M215 G23 N25 R26 G27 I28 R51 R57 E77 V78 N106 G108 I109 I167 S169 Y188 K192 P218 G219 W220 V221 T223 M225
BS02 EDO A S159 Y178 S169 Y188
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3wxb, PDBe:3wxb, PDBj:3wxb
PDBsum3wxb
PubMed26206323
UniProtF1N9C1

[Back to BioLiP]