Structure of PDB 3wwr Chain A

Receptor sequence
>3wwrA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
DSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGSVTL
ELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIE
VIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVG
LKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRC
RHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVL
EVFG
3D structure
PDB3wwr Synthesis and biological activities of vitamin D3 derivatives with cyanoalkyl side chain at C-2 position.
ChainA
Resolution3.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AJ A Y143 D144 Y147 I271 R274 S275 S278 C288 H397 Y26 D27 Y30 I102 R105 S106 S109 C119 H228
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3wwr, PDBe:3wwr, PDBj:3wwr
PDBsum3wwr
PubMed25500068
UniProtP11473|VDR_HUMAN Vitamin D3 receptor (Gene Name=VDR)

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