Structure of PDB 3wwj Chain A

Receptor sequence
>3wwjA (length=320) Species: 1042534 (Arthrobacter sp. KNK168) [Search protein sequence]
VYTHDTGLDYITYSDYELDPANPLAGGAAWIEGAFVPPSEARISIFDQGF
YTSDATYTTFHVWNGNAFRLGDHIERLFSNAESIRLIPPLTQDEVKEIAL
ELVAKTELREAMVTVTITRGYSSTPFERDITKHRPQVYMSACPYQWIVPF
DRIRDGVHLMVAQSVRRTPRSSIDPQVKNFQWGDLIRAIQETHDRGFELP
LLLDCDNLLAEGPGFNVVVIKDGVVRSPGRAALPGITRKTVLEIAESLGH
EAILADITPAELYDADEVLGCSTGGGVWPFVSVDGNSISDGVPGPVTQSI
IRRYWELNVEPSSLLTPVQY
3D structure
PDB3wwj A new target region for changing the substrate specificity of amine transaminases.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y67 K188 E221 L243
Catalytic site (residue number reindexed from 1) Y57 K178 E211 L233
Enzyme Commision number 2.1.6.18
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A R86 K188 E221 G224 F225 L243 G245 I246 T247 T283 R76 K178 E211 G214 F215 L233 G235 I236 T237 T273
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3wwj, PDBe:3wwj, PDBj:3wwj
PDBsum3wwj
PubMed26030619
UniProtF7J696

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