Structure of PDB 3wuw Chain A

Receptor sequence
>3wuwA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDGETRNMKASAQTYRENLRTALRYYNQSEAGSHIIQVMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB3wuw Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 N66 M67 T73 N77 Y84 Y99 D114 Y123 T143 K146 W147 Q155 Y159 W167 Y171 Y7 E63 N66 M67 T73 N77 Y84 Y99 D114 Y123 T143 K146 W147 Q155 Y159 W167 Y171
External links
PDB RCSB:3wuw, PDBe:3wuw, PDBj:3wuw
PDBsum3wuw
PubMed24563253
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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