Structure of PDB 3wrk Chain A

Receptor sequence
>3wrkA (length=391) Species: 303 (Pseudomonas putida) [Search protein sequence]
NLAPLPPHVPEHLVFDFDMYNPSNLSAGVQEAWAVLQESNVPDLVWTRCN
GGHWIATRGQLIREAYEDYRHFSSECPFIPREQRQFRALANQVVGMPVVD
KLENRIQELACSLIESLRPQGQCNFTEDYAEPFPIRIFMLLAGLPEEDIP
HLKYLTDQMTRPDGSMTFAEAKEALYDYLIPIIEQRRQKPGTDAISIVAN
GQVNGRPITSDEAKRMCGLLLVGGLDTVVNFLSFSMEFLAKSPEHRQELI
ERPERIPAACEELLRRFSLVADGRILTSDYEFHGVQLKKGDQILLPQMLS
GLDERENACPMHVDFSRQKVSHTTFGHGSHLCLGQHLARREIIVTLKEWL
TRIPDFSIAPGAQIQHKSGIVSGVQALPLVWDPATTKAVHH
3D structure
PDB3wrk Structure of P450cam intermedite
ChainA
Resolution2.609 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R186 G248 D251 T252 V253 C357 L358 G359 E366 V396
Catalytic site (residue number reindexed from 1) R161 G223 D226 T227 V228 C332 L333 G334 E341 V371
Enzyme Commision number 1.14.15.1: camphor 5-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A R112 L244 L245 G248 G249 T252 D297 R299 Q322 T349 F350 G351 H355 C357 G359 R87 L219 L220 G223 G224 T227 D272 R274 Q297 T324 F325 G326 H330 C332 G334
BS02 CAM A F87 G248 F78 G223
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018683 camphor 5-monooxygenase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0019383 (+)-camphor catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3wrk, PDBe:3wrk, PDBj:3wrk
PDBsum3wrk
PubMed
UniProtP00183|CPXA_PSEPU Camphor 5-monooxygenase (Gene Name=camC)

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