Structure of PDB 3wn5 Chain A

Receptor sequence
>3wn5A (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
ELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEEPEVKFNWYVDGV
EVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNDALPKPI
EETISKAKGQPREPQVYTLPPSRCELTKNQVSLSCAVKGFYPSDIAVEWE
SNGQPENNYKTTPPVLDSDGSFFLVSKLTVDKSRWQQGNVFSCSVMHEAL
HNHYTQKSLSLS
3D structure
PDB3wn5 Crystal structure of a novel asymmetrically engineered Fc variant with improved affinity for Fc gamma Rs.
ChainA
Resolution2.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA A F241 F243 F9 F11
BS02 GAL A P245 K246 E258 P13 K14 E26
External links
PDB RCSB:3wn5, PDBe:3wn5, PDBj:3wn5
PDBsum3wn5
PubMed24334029
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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