Structure of PDB 3wmx Chain A

Receptor sequence
>3wmxA (length=310) Species: 381666 (Cupriavidus necator H16) [Search protein sequence]
GKPKILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHVHLTHEML
NATDRGELATVVERHGITQVYLLAAALSATGEKAPQWAWNLNMTSLLNVL
ELARQTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEG
WCRWYHANHGVDVRSVRYPGLISHKTPPGGGTTDYAVDIFHAAVTGEPYT
CFLKEDEALPMMYMPDAIRATIELMEAPADKLSERGSYNIAGMSFTPAQI
AAAIREQVPGFQIRYEPDYRQAIAQGWPDSIDDSVARADWGWKAQYGLKE
MVADMLANLK
3D structure
PDB3wmx Binding of NAD+ and L-Threonine Induces Stepwise Structural and Flexibility Changes in Cupriavidus necator L-Threonine Dehydrogenase
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G12 G15 Q16 I17 D38 V39 N54 A55 L76 A77 A78 P117 S119 Y144 K148 Y171 L174 G9 G12 Q13 I14 D35 V36 N51 A52 L73 A74 A75 P114 S116 Y141 K145 Y168 L171
BS02 THR A L80 S81 Y144 G184 T186 W280 L77 S78 Y141 G181 T183 W277
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008743 L-threonine 3-dehydrogenase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006567 threonine catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3wmx, PDBe:3wmx, PDBj:3wmx
PDBsum3wmx
PubMed24558034
UniProtQ0K312

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