Structure of PDB 3wkh Chain A

Receptor sequence
>3wkhA (length=410) Species: 29549 (Rhodothermus marinus) [Search protein sequence]
TETIPDVRRLRALQAEVHEELTENILKFWATRTHDPVHGGFVGRVGPDGR
PHPEAPRGAILNARILWTFAAAYRQLGTPLYREMAERAYRYFVRHFVDAE
HGGVYWMVAADGRPLDTRKHVYAQSFAIYALSEWHRATGGEAALALARSI
YDLIETHCADRVHGGYVEACDRAWRPLEDARLSAKDAPEPRSMNTHLHVL
EAYANLYRVWPETELAARLQALIELFLRAIYHPATGHLILFFDERWRPRS
RAVSFGHDIEASWLLLEAVDVLGQATLRPRVQQASLHLARATLAEGRAPD
GSLYYEIGEQGHLDTDRHWWPQAEALVGFLNAYQESGEVLFYEAAEDVWR
YIRERQRDTRGGEWFARVRDDGAPYPDDKVDFWKGPYHNGRACLEAIQRL
RHLLEHVRSR
3D structure
PDB3wkh Structural Insights into the Epimerization of beta-1,4-Linked Oligosaccharides Catalyzed by Cellobiose 2-Epimerase, the Sole Enzyme Epimerizing Non-anomeric Hydroxyl Groups of Unmodified Sugars
ChainA
Resolution1.644 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.1.3.11: cellobiose epimerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA A R66 Y124 N196 H200 H259 W322 W385 H390 R64 Y122 N194 H198 H257 W320 W383 H388
BS02 GAL A S185 D188 W385 S183 D186 W383
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0047736 cellobiose epimerase activity
GO:0050121 N-acylglucosamine 2-epimerase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006044 N-acetylglucosamine metabolic process
GO:0006051 N-acetylmannosamine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3wkh, PDBe:3wkh, PDBj:3wkh
PDBsum3wkh
PubMed24362032
UniProtF8WRK9|CEEP_RHOMR Cellobiose 2-epimerase (Gene Name=ce)

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