Structure of PDB 3we0 Chain A

Receptor sequence
>3we0A (length=540) Species: 306 (Pseudomonas sp.) [Search protein sequence]
KKPITIFGPDFPFAFDDWLEHPAGLGSIPAARHGEEVAIVGAGIAGLVAA
YELMKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFY
HYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQEVTD
AWADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATS
KAFAKLSFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVMTNCDDHQHLV
VGGVEQVPQGIWRHVPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGR
LAVTDNWGDCRHYAAVLTTCQSWLLTTQIDCEESLFSQKMWMALDRTRYM
QSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLFDNGDDKPGV
ICLSYAWHPVEKRVQLALDALKKIYPKTDIAGHIIGDPITISWEADPHFL
GAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAGDDVSWTPAWVEGA
VQTSLNAVWGIMNHFGGKTHADNPGPGDVFDEIGQIALAD
3D structure
PDB3we0 Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E245 K365
Catalytic site (residue number reindexed from 1) E234 K354
Enzyme Commision number 1.13.12.3: tryptophan 2-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A V51 G52 G54 I55 A56 E75 A76 G81 R82 G99 G100 R102 F103 V301 C331 I340 W463 H468 F469 A472 G507 D508 A515 W516 V517 A520 V40 G41 G43 I44 A45 E64 A65 G70 R71 G88 G89 R91 F92 V290 C320 I329 W443 H448 F449 A452 G487 D488 A495 W496 V497 A500
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0001716 L-amino-acid oxidase activity
GO:0004497 monooxygenase activity
GO:0016491 oxidoreductase activity
GO:0050067 lysine 2-monooxygenase activity
GO:0050361 tryptophan 2-monooxygenase activity
Biological Process
GO:0009063 amino acid catabolic process
GO:0009851 auxin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3we0, PDBe:3we0, PDBj:3we0
PDBsum3we0
PubMed24693490
UniProtB3IVI6

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