Structure of PDB 3wby Chain A

Receptor sequence
>3wbyA (length=271) Species: 290633 (Gluconobacter oxydans 621H) [Search protein sequence]
EAQTVISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVATARLY
KNEEGVGKGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDL
YLIHWPMPAQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATG
VVPVVNQIELHPDFQQRALREFHEKHNIRTESWRPLGKGRVLSDERIGKI
AEKHSRTPAQVVIRWHLQNGLIVIPKSVNPKRLAENLDVFGFVLDADDMQ
AIEQMDRKDGRMGADPNTAKF
3D structure
PDB3wby Crystal structure of Gox0644 D53A mutant in complex with NADPH
ChainA
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A53 Y58 K79 H112
Catalytic site (residue number reindexed from 1) A45 Y50 K71 H104
Enzyme Commision number 1.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP A E31 W113 W191 R192 P193 L194 K196 L200 K234 S235 R240 E243 N244 A272 E23 W105 W183 R184 P185 L186 K188 L192 K226 S227 R232 E235 N236 A264
BS02 NDP A H20 T21 H12 T13
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050580 2,5-didehydrogluconate reductase activity

View graph for
Molecular Function
External links
PDB RCSB:3wby, PDBe:3wby, PDBj:3wby
PDBsum3wby
PubMed
UniProtQ5FT75

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