Structure of PDB 3w57 Chain A

Receptor sequence
>3w57A (length=111) Species: 52904 (Scophthalmus maximus) [Search protein sequence]
HMQLRLYNLRVRGLPSDLMGITDGYVKVFCGSANLGETSVNHNNANPWWT
EEFSHFKAQENDILRLEVHDEDTFFDDLLGVCQRQIKVGTHEHDCYLKEG
GTLHYMYTLSV
3D structure
PDB3w57 Defining the interaction of perforin with calcium and the phospholipid membrane.
ChainA
Resolution1.662 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D35 D41 D88 E89 D90 D17 D23 D70 E71 D72
BS02 CA A D35 D88 D90 D95 D17 D70 D72 D77
BS03 CA A I39 D41 N61 I21 D23 N43
Gene Ontology
Molecular Function
GO:0022829 wide pore channel activity
GO:0046872 metal ion binding
Biological Process
GO:0001771 immunological synapse formation
GO:0001913 T cell mediated cytotoxicity
GO:0051607 defense response to virus
GO:0055085 transmembrane transport

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3w57, PDBe:3w57, PDBj:3w57
PDBsum3w57
PubMed24070258
UniProtE2FYL5

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