Structure of PDB 3w3c Chain A

Receptor sequence
>3w3cA (length=116) Species: 42897 (Shigella flexneri 2a) [Search protein sequence]
EHSIRELGIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEIIS
LFPIASELNFNDYKILFNYYKGLEKANESLSSTLPILKEEIKDLDTNLPP
DIYKKEILNIIKKSKN
3D structure
PDB3w3c Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
ChainA
Resolution2.431 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S150 Y151 K152 R162 T166 S20 Y21 K22 R32 T36 PDBbind-CN: Kd=16nM
BS02 dna A K164 R167 N189 F190 K34 R37 N59 F60 PDBbind-CN: Kd=16nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3w3c, PDBe:3w3c, PDBj:3w3c
PDBsum3w3c
PubMed23985969
UniProtP0A247|VIRB_SHIFL Virulence regulon transcriptional activator VirB (Gene Name=virB)

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